Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (14): 2147-2152.doi: 10.3969/j.issn.2095-4344.2017.14.003

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Different bone cement implantation ways for osteoporotic vertebral compression fractures

Zhou Wei1, Liu Gui-sheng2, Zhou Li-ping3, Gao Fang3, Liu Xun-wei3, Xie Zhi-yong3   

  1. 1 Department of Interventional Radiology, Juxian People’s Hospital, Juxian 276500, Shandong Province, China; 2 Department of Radiology, Yuncheng County People’s Hospital, Yuncheng 274700, Shandong Province, China; 3 Department of Medical Imaging, General Hospital of Jinan Military Region of Chinese PLA, Jinan 250031, Shandong Province, China
  • Received:2016-12-17 Online:2017-05-18 Published:2017-06-10
  • Contact: Xie Zhi-yong, Associate chief physician, Department of Medical Imaging, General Hospital of Jinan Military Region of Chinese PLA, Jinan 250031, Shandong Province, China
  • About author:Zhou Wei, Attending physician, Department of Interventional Radiology, Juxian People’s Hospital, Juxian 276500, Shandong Province, China
  • Supported by:

    the National High-Tech Research and Development Program of China (863 Program), No. 2013AA032203

Abstract:

BACKGROUND: After the treatment of osteoporotic vertebral compression fractures with bone cement implantation, deteriorative osteoporosis and the distance augment between bone cement and bones result in a decrease in bone cement-bone interface compression strength and torsion strength, and then the bone cement tends to displace, which is easy to cause a secondary vertebral fracture.
OBJECTIVE: To investigate the clinical efficacy of bone cement implantation via three approaches on osteoporotic vertebral compression fractures.
METHODS: Sixty patients with single osteoporotic vertebral compression fracture were treated with vertebroplasty, percutaneous kyphoplasty or fraction cement vertebroplasty. All data were collected to analyze the correlation between the bone cement morphology and treatment method, and to detect the visual analogue scale, Oswestry disability index, Cobb angle and incidence of secondary vertebral fractures.
RESULTS AND CONCLUSION: The visual analogue scale scores, Oswestry disability index, and Cobb angle in the three groups were significantly improved after treatment (P < 0.05). All above indicators showed no significant difference among groups at each time point after treatment, suggesting that these three kinds of treatments exert the same effects on pain relief, functional recovery, preventing the vertebral height loss and maintaining spinal mechanical properties. Bone cement displacement and secondary vertebral fracture occurred after clotted cement implantation. Therefore, mixed and trabecular-shaped grafts are preferred, aiming to achieve good long-term treatment outcomes in osteoporotic vertebral compression fractures.

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Osteoporotic Fractures, Fractures, Compression, Vertebroplasty, Acrylic Resins, Tissue Engineering

CLC Number: